B-Cell Activating Factor

A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.

Also Known As:

B Cell Activating Factor; B Lymphocyte Stimulator; B-Lymphocyte Activating Factor; BLyS Protein; CD257 Antigen; TALL-1 Protein; THANK Protein; TNF Superfamily, Member 13b; TNF and APOL-Related Leukocyte Expressed Ligand 1; TNFSF13B Protein; Activating Factor, B-Cell; Activating Factor, B-Lymphocyte; Antigen, CD257; B Lymphocyte Activating Factor; TALL 1 Protein; TNF and APOL Related Leukocyte Expressed Ligand 1; Antigens, CD257; BAFF Ligand; CD257 Antigens; Tumor Necrosis Factor Ligand Superfamily Member 13b

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - B-Cell Activating Factor: 737
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Tumor Necrosis Factors: 152
        B-Cell Activating Factor: 737
  - Glycoproteins: 24834
    - B-Cell Activating Factor: 737
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - B-Cell Activating Factor: 737
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Tumor Necrosis Factors: 152
        B-Cell Activating Factor: 737
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Tumor Necrosis Factors: 152
      - B-Cell Activating Factor: 737

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Disease

Drug/Important Bio-Agent (IBA)